mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia
نویسندگان
چکیده
منابع مشابه
mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.
Bacillus anthracis is surrounded by an antiphagocytic polypeptide capsule composed of poly gamma-D-glutamic acid (gammaDPGA). gammaDPGA has been identified recently as a potential target for vaccine development. Studies of the role of gammaDPGA in disease have been hampered by the poor Ab response to this antigen and the lack of immunochemical reagents. As a consequence, neither the extent of g...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2004
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0401351101